1. Association between diesel exhaust exposure and mitochondrial ...
Association between diesel exhaust exposure and mitochondrial DNA methylation. / Seow, Wei Jie; Hu, Wei; Dai, Yufei et al. In: Carcinogenesis, Vol. 43, No. 12, ...
Objectives: Diesel exhaust is an established human carcinogen, however the mechanisms by which it leads to cancer development are not fully understood. Mitochondrial dysfunction is an established contributor to carcinogenesis. Recent studies have improved our understanding of the role played by epigenetic modifications in the mitochondrial genome on tumorigenesis. In this study, we aim to evaluate the association between diesel engine exhaust (DEE) exposure with mitochondrial DNA (mtDNA) methylation levels in workers exposed to DEE. Methods: The study population consisted of 53 male workers employed at a diesel engine manufacturing facility in Northern China who were routinely exposed to diesel exhaust in their occupational setting, as well as 55 unexposed male control workers from other unrelated factories in the same geographic area. Exposure to DEE, elemental carbon, organic carbon, and particulate matter (PM2.5) were assessed. mtDNA methylation for CpG sites (CpGs) from seven mitochondrial genes (D-Loop, MT-RNR1, MT-CO2, MT-CO3, MT-ATP6, MT-ATP8, MT-ND5) was measured in blood samples. Linear regression models were used to estimate the associations between DEE, elemental carbon, organic carbon and PM2.5exposures with mtDNA methylation levels, adjusting for potential confounders. Results: DEE exposure was associated with decreased MT-ATP6 (difference = -35.6%, P-value = 0.019) and MT-ATP8 methylation (difference = -30%, P-value = 0.029) compared to unexposed controls. Expos...
2. Mitochondrial DNA Copy Number and Chronic Lymphocytic ... - Julkari
Näytä suppeat kuvailutiedot. Mitochondrial DNA Copy Number and Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma Risk in Two Prospective Studies.
Näytä suppeat kuvailutiedot
3. proteinase-free DNA replication machinery for in vitro and in vivo ...
29 apr 2020 · A proteinase-free reciprocal DNA replication machinery is developed by exploiting the synergistic cross-activation between hybridization chain reaction (HCR) ...
Abstract. The construction of robust, modular and compact DNA machinery facilitates us to build more intelligent and ingenious sensing strategies in comple
4. Jie Hu (胡杰) - Google Scholar
Suzhou DiYinAn Biotech Co., Ltd. Verified email at sz-dna.cn. Point-of-care diagnosticsMicrofluidics & NanotechnologiesSensors & Actuators.
Suzhou DiYinAn Biotech Co., Ltd. - Cited by 4,126 - Point-of-care diagnostics - Microfluidics & Nanotechnologies - Sensors & Actuators
5. Jie Hu (胡杰) - Google Scholar
X Xu, A Akay, H Wei, SQ Wang, B Pingguan ... A wearable microfluidic device for rapid detection of HIV-1 DNA using recombinase polymerase amplification.
See AlsoFry99.CimSuzhou DiYinAn Biotech Co., Ltd. - อ้างอิงโดย 4,126 รายการ - Point-of-care diagnostics - Microfluidics & Nanotechnologies - Sensors & Actuators
6. Jie Hu
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7. Wei Jie Seow - Google Scholar
Telomere length in white blood cell DNA and lung cancer: a pooled analysis of three prospective cohorts. WJ Seow, RM Cawthon, MP Purdue, W Hu, YT Gao, WY Huang, ...
Saw Swee Hock School of Public Health - Cited by 2,762 - Epidemiology
8. Selaus tekijän mukaan "Seow, Wei Jie" - Julkari
Pooled Analysis of Mitochondrial DNA Copy Number and Lung Cancer Risk in Three Prospective Studies . Kim, Christopher; Bassig, Bryan A.; Seow, Wei Jie; Hu, Wei ...
Seow, Wei Jie; Cawthon, Richard M.; Purdue, Mark P.; Hu, Wei; Gao, Yu-Tang; Huang, Wen-Yi; Weinstein, Stephanie J.; Ji, Bu-Tian; Virtamo, Jarmo; Hosgood, H. Dean, III; Bassig, Bryan A.; Shu, Xiao-Ou; Cai, Qiuyin; Xiang, Yong-Bing; Min, Shen; Chow, Wong-Ho; Berndt, Sonja I.; Kim, Christopher; Lim, Unhee; Albanes, Demetrius; Caporaso, Neil E.; Chanock, Stephen; Zheng, Wei; Rothman, Nathaniel; Lan, Qing CANCER RESEARCH : 15 (26.09.2014)